The Tennis star made it to the last 32 on Wednesday after saying she believes her opponent express fear anytime they want to play against her.
The former World No.1 and five-time major winner pulled off a 6-7 (4/7), 6-4, 6-1 win over Timea Babos of Hungary.
It was her second three-set match, having seen off World.2 Simona Halep on Monday in what was her first Grand Slam match since being hit with a 15-month doping ban.
The 2006 champion, and guaranteed arena-filler, needed a wild card to play in New York after her prolonged absence from the sport had left her with a world ranking of 146.
“I definitely feel the respect from the athletes,” Sharapova said.